Scientists Find the First sign of Alzheimer’s
First Sign Of Alzheimer’s Disease has been Found
The first signs of Alzheimer’s should not be confused with AIMM’s “Age Induced Medication Mistakes is a normal part of aging. Alzheimer’s is a disease that effects the physiology of the brain. There is no cure at this time. This being said, there are drugs that have been shown to slow the progression. The early these treatments start, the more likely they are to be successful. For this reason, finding the first sign of Alzheimer’s is key to early treatment.
Imnprtant to realize the past consensus is that memory loss as well as cognitive decline, are the fist signs of Alzheimer’s or Dementia. These have been used to measure the first indication of Alzheimer’s. This is no longer the case. A recent study has uncovered the drop in the brains glucose level may be the First Sign Of Alzheimer’s.
Discovery of the First Sign Of Dementia means early treatment options
These levels can show as the first symptom. The Great news, they believe they have discovered a method that will to stop the glucose dropping. If this works, it could potentially prevent Dementia before it begins. That is to say many healthcare professionals have seen an association between dropping brain glucose levels concurrent with the onset of Alzheimer’s disease. With this in mind, a newly release study by the journal Translational Psychiatry has shown remarkable data.
- Translational Psychiatry is a peer-reviewed medical journal published by Nature Publishing Group. It is a sister journal to the better-known Molecular Psychiatry. While both journals cover the larger field of biological psychiatry, Translational Psychiatry is more focused on translational aspects of research
In addition the Study has found that declining energy levels are a direct trigger. This leads to the cognitive impairments associated with the disease. Subsequently the study theories’ that may explain why diabetes, a condition in which glucose cannot enter the cells, is a high risk factor for dementia. The study has shown that a protein known as p38 might prevent this from happening
“The findings are very exciting,” said the Dr. Domenico Praticò . “There is now a lot of evidence to suggest that p38 is involved in the development of the disease.”
The study is a group comprised of mice that have had their brain’s deprived glucose.
It can be said he results have been observed. Hence, the Researchers prediction of the mice exhibited signs of decline had been confirmed. For the fear that nerve cells and their networks began to break down. Not surprisingly, the glucose-deprived mice did much worse than healthy mice in memory testing’s. These same mice, in addition, had elevated levels of phosphorylated tau. In addition, there is big increased amounts of cell death. These are two of the most obvious signs.
First of all the study also identified p38 as a possible candidate for the development of a drug to prevent the onset of cognitive decline. Furthermore, this is caused by low glucose levels. According to the research, this protein is naturally made in the body as a response to glucose deprivation. Further more, research will further investigate p38’s role in memory impairments.
Preventing Alzheimer’s disease is a major goal for scientists around the world, and this year there have been several breakthroughs in this effort. For example, this July a team from Flinders University in Adelaide Australia in partnership with a research team at the Institute of Molecular Medicine, and University of California, Irvine released their efforts on creating a drug that could prevent brain protein buildup, the main hallmark of the disease. According to the research, these findings could lead to a vaccine against Alzheimer’s in as short as 5-6 years.
In fact Johns Hopkins University School of Medicine are attempting to make a pill to prevent the accumulation of toxic molecules in the brain. These are the same molecules that eventually form brain plaques. Discovery of the First Sign Of Alzheimer’s means early treatment options and a longer and better life.