Brushing your teeth, flossing, and rinsing regularly helps you maintain a healthy smile, and ward off gum disease. The accumulation of mouth bacteria not only affects your oral health, but also your joint health. A recent study in Science Translational Medicine found bacteria that causes gum disease may also trigger the onset of inflammation in rheumatoid arthritis (RA).
RA starts in small joints in one’s hands and feet. It will cause inflammation, swelling, pain as well as a stiffness. New Researcher has shown a correlation between RA and gum disease. Previous studies has uncovered a connection with tooth loss and the risk of developing Rheumatoid arthritis. In fact the worse the tooth loss, the greater the risk of RA in addition to other kinds of joint inflammation.
A team of scientist have done research to find out if RA may have a bacterial cause, and whether the specific bacteria could originate from one’s own mouth.
Blood samples were collected from 200 Individuals that had gum disease as well as 200 healthy men and women.
The researchers also obtained blood and joint fluid samples from another sample of approximately 200 people who met standard disease criteria for RA.
The composition of the gum fluid was analyzed to see how it differed between healthy people and those with gum disease. Similarities between blood and joint fluid samples of people with RA were also observed.
The findings revealed the gum fluid of people with gum disease contained high levels of citrullinated proteins. Citrullination is a protein in everyone. However, in patients with RA, the process is overactive, resulting in abnormal levels of the proteins. They’re known to cause an immune response in people with RA. There was lots of the proteins in the fluid. It is common knowledge that people produce antibodies against these proteins. These are known as anti-cyclic citrullinated peptides.
The studies have provided data that suggests the bacteria could trigger RA, This is still being studied and is not definitive. The Fact of the matter is that the onset of the disease can take 10 years or longer. In is important to note that not everyone with gum disease develops rheumatoid arthritis. This being said, and not everyone with RA has gum disease.
However, the findings do provide a better understanding of causes of autoimmune disease, like RA, which currently have no definitive cause. In the meantime, brushing your teeth could help prevent tooth decay, and gum diseases, and potentially Rheumatoid arthritis .
Biologics are available to treat the symptoms of rheumatoid arthritis.
Biologics are genetically-engineered proteins derived from human genes. Designed to inhibit specific components of the immune system that causes or leads to inflammation.
They are all very pricey. In fact some Biologics cost more than $6,000 for 1 weeks supply. Taking into account the evidence for effectiveness and safety, In addition if you need a biologic drug to treat your rheumatoid arthritis. Med-Q Medication Compliance System can help you manage your meds. Med-Q Pill Box hase chosen the following as Consumer Reports Best Buy Drugs:
Studies show that these three medications are as effective as the other biologics for relieving rheumatoid arthritis symptoms,. The have also been shown to have a lesser rates of withdrawal
Moreover the study showed that men and women taking biologics had a higher chance of a risk of serious side effects. The study found 12-13% had life-threatening allergic reaction. As a result, they may experienced, infections. Moreover life-threatening infections include tuberculosis, pneumonia, or staph in addition to fungal infections. For Instances some of the lesser effects include stomach pain as well as nausea.